Bradbury, Barton J

Synthesis and complement inhibitory activity of B/C/D-ring analogues of the fungal metabolite 6,7-diformyl-3',4',4a',5',6',7',8',8a'-octahydro-4,6',7'-trihydroxy- 2',5',5',8a'-tetramethylspiro[1'(2'H)-naphthalene-2(3H)-benzofuran]. [electronic resource] - Journal of medicinal chemistry Jun 2003 - 2697-705 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-2623

10.1021/jm0204284 doi


Animals
Complement C3a--biosynthesis
Complement C5a--biosynthesis
Hemolysis--drug effects
Humans
In Vitro Techniques
Rabbits
Sesquiterpenes--chemical synthesis
Structure-Activity Relationship