Lee, Kyeong

Utilization of a beta-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides. [electronic resource] - Journal of medicinal chemistry Jun 2003 - 2621-30 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm030049q doi


Adaptor Proteins, Signal Transducing
Cell Line
Crystallography, X-Ray
Cyclization
Drug Design
GRB2 Adaptor Protein
Humans
Ligands
Models, Molecular
Molecular Conformation
Molecular Mimicry
Peptides, Cyclic--chemical synthesis
Phosphotyrosine--chemistry
Proteins--metabolism
Structure-Activity Relationship
src Homology Domains