Utilization of a beta-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides. [electronic resource]
- Journal of medicinal chemistry Jun 2003
- 2621-30 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-2623
10.1021/jm030049q doi
Adaptor Proteins, Signal Transducing Cell Line Crystallography, X-Ray Cyclization Drug Design GRB2 Adaptor Protein Humans Ligands Models, Molecular Molecular Conformation Molecular Mimicry Peptides, Cyclic--chemical synthesis Phosphotyrosine--chemistry Proteins--metabolism Structure-Activity Relationship src Homology Domains