TY  - GEN
AU  - de Kleijn,Ester D
AU  - de Groot,Ronald
AU  - Hack,C Erik
AU  - Mulder,Paul G H
AU  - Engl,Werner
AU  - Moritz,Berta
AU  - Joosten,Koen F M
AU  - Hazelzet,Jan A
TI  - Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: a randomized, double-blinded, placebo-controlled, dose-finding study
SN  - 0090-3493
PY  - 2003///0709
KW  - Anticoagulants
KW  - pharmacology
KW  - Child
KW  - Child, Preschool
KW  - Dose-Response Relationship, Drug
KW  - Double-Blind Method
KW  - Female
KW  - Fibrin Fibrinogen Degradation Products
KW  - metabolism
KW  - Humans
KW  - IgA Vasculitis
KW  - drug therapy
KW  - Infant
KW  - Interleukin-6
KW  - blood
KW  - Male
KW  - Meningococcal Infections
KW  - Netherlands
KW  - epidemiology
KW  - Proportional Hazards Models
KW  - Protein C
KW  - Regression Analysis
KW  - Shock, Septic
KW  - Survival Rate
N1  - Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1097/01.CCM.0000072121.61120.D8
ER  -