de Kleijn, Ester D <br/><br/>
Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: a randomized, double-blinded, placebo-controlled, dose-finding study.  [electronic resource] 

 -  Critical care medicine  Jun 2003 
 - 1839-47 p.  digital 
<br/><br/> Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0090-3493 
<br/><br/><label>Standard No.: </label>10.1097/01.CCM.0000072121.61120.D8  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Anticoagulants--pharmacology<br/>Child<br/>Child, Preschool<br/>Dose-Response Relationship, Drug<br/>Double-Blind Method<br/>Female<br/>Fibrin Fibrinogen Degradation Products--metabolism<br/>Humans<br/>IgA Vasculitis--drug therapy<br/>Infant<br/>Interleukin-6--blood<br/>Male<br/>Meningococcal Infections--drug therapy<br/>Netherlands--epidemiology<br/>Proportional Hazards Models<br/>Protein C--pharmacology<br/>Regression Analysis<br/>Shock, Septic--drug therapy<br/>Survival Rate