TY - GEN AU - Pérez,María José AU - Cederbaum,Arthur I TI - Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells SN - 0270-9139 PY - 2003///0618 KW - Antioxidants KW - pharmacology KW - Arachidonic Acid KW - poisoning KW - Buthionine Sulfoximine KW - Carcinoma, Hepatocellular KW - pathology KW - Cysteine Endopeptidases KW - physiology KW - Cytochrome P-450 CYP2E1 KW - metabolism KW - Drug Synergism KW - Endopeptidases KW - Humans KW - Iron KW - Leupeptins KW - Lipid Peroxides KW - Liver Neoplasms KW - Lysosomes KW - enzymology KW - Membrane Potentials KW - drug effects KW - Mitochondria, Liver KW - Multienzyme Complexes KW - antagonists & inhibitors KW - Proteasome Endopeptidase Complex KW - Tumor Cells, Cultured KW - Tyrosine KW - analogs & derivatives N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1053/jhep.2003.50228 ER -