TY - GEN AU - Marques-Soares,Cristina AU - Dijols,Sylvie AU - Macherey,Anne-Christine AU - Wester,Michael R AU - Johnson,Eric F AU - Dansette,Patrick M AU - Mansuy,Daniel TI - Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymes SN - 0006-2960 PY - 2003///0716 KW - Anti-Infective Agents KW - pharmacology KW - Aryl Hydrocarbon Hydroxylases KW - chemistry KW - Biochemistry KW - methods KW - Cells, Cultured KW - Crystallography, X-Ray KW - Cytochrome P-450 CYP2C19 KW - Cytochrome P-450 CYP2C8 KW - Cytochrome P-450 CYP2C9 KW - Cytochrome P-450 Enzyme System KW - Cytochrome P450 Family 2 KW - Dose-Response Relationship, Drug KW - Humans KW - Inhibitory Concentration 50 KW - Kinetics KW - Liver KW - metabolism KW - Microsomes KW - Mixed Function Oxygenases KW - Models, Chemical KW - Oxygen KW - Progesterone KW - Protein Binding KW - Protein Folding KW - Protein Structure, Tertiary KW - Steroid 21-Hydroxylase KW - Substrate Specificity KW - Sulfaphenazole KW - Sulfonamides KW - Ultraviolet Rays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/bi027391+ ER -