Klisovic, Dino D
Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines. [electronic resource]
- Investigative ophthalmology & visual science Jun 2003
- 2390-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 0146-0404
Standard No.: 10.1167/iovs.02-1052 doi
Subjects--Topical Terms: Antibiotics, Antineoplastic--pharmacology Apoptosis--drug effects Blotting, Western Butyrates--pharmacology Caspase 3 Caspases--metabolism Cell Cycle Proteins--genetics Cell Division--drug effects Cyclin-Dependent Kinase Inhibitor p21 Cyclin-Dependent Kinase Inhibitor p27 Cyclins--genetics Depsipeptides Dose-Response Relationship, Drug Enzyme Inhibitors--pharmacology Fas Ligand Protein Flow Cytometry Histone Deacetylase Inhibitors Humans Hydroxamic Acids--pharmacology Melanoma--genetics Membrane Glycoproteins--genetics Peptides, Cyclic--pharmacology Proto-Oncogene Proteins--genetics Proto-Oncogene Proteins c-bcl-2--genetics RNA, Messenger--metabolism Reverse Transcriptase Polymerase Chain Reaction Tumor Cells, Cultured Tumor Suppressor Proteins--genetics Uveal Neoplasms--genetics bcl-2-Associated X Protein fas Receptor--genetics