TY - GEN AU - Kuroda,Junya AU - Kimura,Shinya AU - Segawa,Hidekazu AU - Kobayashi,Yutaka AU - Yoshikawa,Toshikazu AU - Urasaki,Yoshimasa AU - Ueda,Takanori AU - Enjo,Fumio AU - Tokuda,Harukuni AU - Ottmann,Oliver G AU - Maekawa,Taira TI - The third-generation bisphosphonate zoledronate synergistically augments the anti-Ph+ leukemia activity of imatinib mesylate SN - 0006-4971 PY - 2003///1017 KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - metabolism KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Benzamides KW - Cell Division KW - Diphosphonates KW - Drug Synergism KW - HL-60 Cells KW - Hematopoietic Stem Cells KW - cytology KW - Humans KW - Imatinib Mesylate KW - Imidazoles KW - K562 Cells KW - Leukemia, Myelogenous, Chronic, BCR-ABL Positive KW - drug therapy KW - Mice KW - Mice, Inbred NOD KW - Mice, SCID KW - Monomeric GTP-Binding Proteins KW - Pamidronate KW - Piperazines KW - Protein Prenylation KW - Pyrimidines KW - Zoledronic Acid N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2003-01-0305 ER -