TY  - GEN
AU  - Teofili,L
AU  - Martini,M
AU  - Luongo,M
AU  - Diverio,D
AU  - Capelli,G
AU  - Breccia,M
AU  - Lo Coco,F
AU  - Leone,G
AU  - Larocca,L M
TI  - Hypermethylation of GpG islands in the promoter region of p15(INK4b) in acute promyelocytic leukemia represses p15(INK4b) expression and correlates with poor prognosis
SN  - 0887-6924
PY  - 2003///0604
KW  - Adult
KW  - Bone Marrow
KW  - metabolism
KW  - Cell Cycle Proteins
KW  - genetics
KW  - Cyclin-Dependent Kinase Inhibitor p15
KW  - Cyclin-Dependent Kinase Inhibitor p16
KW  - DNA Methylation
KW  - DNA Primers
KW  - chemistry
KW  - DNA, Neoplasm
KW  - Dinucleoside Phosphates
KW  - Enzyme Inhibitors
KW  - Female
KW  - Follow-Up Studies
KW  - Gene Expression Regulation, Neoplastic
KW  - Gene Silencing
KW  - Genes, Tumor Suppressor
KW  - Humans
KW  - Immunoenzyme Techniques
KW  - Leukemia, Promyelocytic, Acute
KW  - Male
KW  - Neoplasm Recurrence, Local
KW  - Polymerase Chain Reaction
KW  - Prognosis
KW  - Promoter Regions, Genetic
KW  - RNA, Messenger
KW  - RNA, Neoplasm
KW  - Sulfites
KW  - Survival Rate
KW  - Syndrome
KW  - Treatment Outcome
KW  - Tumor Suppressor Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/sj.leu.2402907
ER  -