Gascoyne, Duncan M

Loss of mitotic spindle checkpoint activity predisposes to chromosomal instability at early stages of fibrosarcoma development. [electronic resource] - Cell cycle (Georgetown, Tex.) - 238-45 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1538-4101


Adaptor Proteins, Signal Transducing
Animals
Cell Cycle Proteins--genetics
Cell Transformation, Neoplastic--genetics
Chromosome Aberrations
Cyclin B--genetics
DNA Damage--genetics
Disease Progression
Fibroma--genetics
Fibrosarcoma--genetics
Genes, cdc--physiology
Genetic Predisposition to Disease--genetics
Mice
Mitosis--genetics
Models, Biological
Mutation--genetics
Saccharomyces cerevisiae Proteins--genetics
Spindle Apparatus--genetics
Tumor Cells, Cultured
Tumor Suppressor Protein p53--genetics