Im, Hee-Jeong

Inhibitory effects of insulin-like growth factor-1 and osteogenic protein-1 on fibronectin fragment- and interleukin-1beta-stimulated matrix metalloproteinase-13 expression in human chondrocytes. [electronic resource] - The Journal of biological chemistry Jul 2003 - 25386-94 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M302048200 doi


Blotting, Western
Bone Morphogenetic Protein 7
Bone Morphogenetic Proteins--pharmacology
Cells, Cultured
Chondrocytes--metabolism
Collagenases--biosynthesis
Culture Media, Conditioned--pharmacology
DNA--metabolism
Dose-Response Relationship, Drug
Down-Regulation
Fibronectins--chemistry
Gene Deletion
Humans
Insulin-Like Growth Factor I--pharmacology
Interleukin-1--chemistry
Luciferases--metabolism
Matrix Metalloproteinase 13
Models, Genetic
Plasmids--metabolism
Polymerase Chain Reaction
Promoter Regions, Genetic
RNA--metabolism
RNA, Messenger--metabolism
Receptor, IGF Type 1--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Temperature
Transfection
Transforming Growth Factor beta
Up-Regulation