TY - GEN AU - Sanishvili,Ruslan AU - Yakunin,Alexander F AU - Laskowski,Roman A AU - Skarina,Tatiana AU - Evdokimova,Elena AU - Doherty-Kirby,Amanda AU - Lajoie,Gilles A AU - Thornton,Janet M AU - Arrowsmith,Cheryl H AU - Savchenko,Alexei AU - Joachimiak,Andrzej AU - Edwards,Aled M TI - Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli SN - 0021-9258 PY - 2003///0814 KW - Biotin KW - biosynthesis KW - Carboxylic Ester Hydrolases KW - chemistry KW - Catalytic Domain KW - Computational Biology KW - Crystallography, X-Ray KW - Electrons KW - Escherichia coli KW - metabolism KW - Escherichia coli Proteins KW - Hydrogen Bonding KW - Kinetics KW - Mass Spectrometry KW - Models, Molecular KW - Phosphoric Diester Hydrolases KW - Protein Conformation KW - Protein Folding KW - Protein Structure, Tertiary N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.M303867200 ER -