Koga, Hironori

Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells. [electronic resource] - Hepatology (Baltimore, Md.) May 2003 - 1086-96 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0270-9139

10.1053/jhep.2003.50186 doi


Antineoplastic Agents--pharmacology
CDC2-CDC28 Kinases
Carcinoma, Hepatocellular
Cell Cycle Proteins--genetics
Chromans--pharmacology
Cyclin E--genetics
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
Cyclin-Dependent Kinases--metabolism
Cyclins--genetics
Down-Regulation
Drug Resistance, Neoplasm
G1 Phase--physiology
Gene Expression Regulation, Neoplastic
Humans
Liver Neoplasms
Protein Binding
Protein Serine-Threonine Kinases--metabolism
RNA, Messenger--analysis
S-Phase Kinase-Associated Proteins
Thiazoles--pharmacology
Thiazolidinediones
Troglitazone
Tumor Cells, Cultured
Tumor Suppressor Proteins--genetics