TY - GEN AU - Borroto,Aldo AU - Ruiz-Paz,Soraya AU - de la Torre,Teresa Villanueva AU - Borrell-Pages,Maria AU - Merlos-Suarez,Anna AU - Pandiella,Atanasio AU - Blobel,Carl P AU - Baselga,Josep AU - Arribas,Joaquin TI - Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain shedding SN - 0021-9258 PY - 2003///0814 KW - ADAM Proteins KW - ADAM17 Protein KW - Animals KW - Biotinylation KW - Blotting, Western KW - CHO Cells KW - Cell Line KW - Cricetinae KW - DNA, Complementary KW - metabolism KW - Endoplasmic Reticulum KW - Enzyme Activation KW - Glycoproteins KW - chemistry KW - HeLa Cells KW - Humans KW - Metalloendopeptidases KW - Microscopy, Confocal KW - Microscopy, Fluorescence KW - Molecular Sequence Data KW - Mutation KW - Precipitin Tests KW - Protein Structure, Tertiary KW - Protein Transport KW - Reverse Transcriptase Polymerase Chain Reaction KW - Transfection KW - Transforming Growth Factor alpha KW - Tumor Cells, Cultured KW - Tumor Necrosis Factor-alpha KW - Zinc KW - alpha 1-Antitrypsin N1 - Publication Type: Journal Article UR - https://doi.org/10.1074/jbc.M301673200 ER -