de Bruyn, Kim M T

The small GTPase Rap1 is activated by turbulence and is involved in integrin [alpha]IIb[beta]3-mediated cell adhesion in human megakaryocytes. [electronic resource] - The Journal of biological chemistry Jun 2003 - 22412-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M212036200 doi


Blood Platelets--physiology
Cell Adhesion--drug effects
Cell Line
Chelating Agents--pharmacology
Egtazic Acid--analogs & derivatives
Enzyme Inhibitors--pharmacology
Fibrinogen--physiology
Humans
Jurkat Cells
K562 Cells
Megakaryocytes--physiology
Platelet Glycoprotein GPIIb-IIIa Complex--physiology
Protein Kinase C--antagonists & inhibitors
Recombinant Proteins--metabolism
Signal Transduction
Stress, Mechanical
Transfection
Tumor Cells, Cultured
rap1 GTP-Binding Proteins--metabolism