Madge, Lisa A
Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis. [electronic resource]
- The Journal of biological chemistry Jun 2003
- 21295-306 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
ISSN: 0021-9258
Standard No.: 10.1074/jbc.M212837200 doi
Subjects--Topical Terms: Amino Acid Chloromethyl Ketones--pharmacology Antineoplastic Agents--pharmacology Apoptosis--drug effects CASP8 and FADD-Like Apoptosis Regulating Protein Carrier Proteins--genetics Caspase 3 Caspase 8 Caspase 9 Caspases--metabolism Cathepsin B--metabolism Cell Nucleus Cells, Cultured Chromones--pharmacology Cycloheximide--pharmacology Cysteine Proteinase Inhibitors--pharmacology Endothelium, Vascular--cytology Enzyme Inhibitors--pharmacology Humans Interleukin-1--pharmacology Intracellular Signaling Peptides and Proteins Morpholines--pharmacology Phosphatidylinositol 3-Kinases--metabolism Phosphoinositide-3 Kinase Inhibitors Protein Serine-Threonine Kinases Protein Synthesis Inhibitors--pharmacology Proto-Oncogene Proteins--genetics Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins c-bcl-2--genetics Retroviridae--genetics Transduction, Genetic Tumor Necrosis Factor-alpha--pharmacology Umbilical Veins--cytology