Cools, Jan <br/><br/>
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.  [electronic resource] 

 -  The New England journal of medicine  Mar 2003 
 - 1201-14 p.  digital 
<br/><br/> Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1533-4406 
<br/><br/><label>Standard No.: </label>10.1056/NEJMoa025217  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Base Sequence<br/>Benzamides<br/>Chromosome Deletion<br/>Chromosomes, Human, Pair 4--genetics<br/>Enzyme Inhibitors--therapeutic use<br/>Female<br/>Humans<br/>Hypereosinophilic Syndrome--drug therapy<br/>Imatinib Mesylate<br/>Male<br/>Middle Aged<br/>Molecular Sequence Data<br/>Piperazines--therapeutic use<br/>Protein-Tyrosine Kinases--antagonists & inhibitors<br/>Pyrimidines--therapeutic use<br/>Recombination, Genetic<br/>Remission Induction--methods