Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxal. [electronic resource]
- Journal of cellular biochemistry Apr 2003
- 1235-46 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0730-2312
10.1002/jcb.10478 doi
3T3 Cells Animals Cells, Cultured Cyclin-Dependent Kinase Inhibitor p21 Cyclins--biosynthesis Diabetes Mellitus--metabolism Drug Interactions Enzyme Inhibitors--pharmacology Growth Inhibitors--pharmacology Humans Insulin-Like Growth Factor I--pharmacology MAP Kinase Kinase Kinase 1 Mice Mitogen-Activated Protein Kinases--analysis Protein Serine-Threonine Kinases--analysis Pyruvaldehyde--pharmacology Signal Transduction--physiology