TY  - GEN
AU  - Parkes,Kevin E B
AU  - Ermert,Philipp
AU  - Fässler,Jürg
AU  - Ives,Jane
AU  - Martin,Joseph A
AU  - Merrett,John H
AU  - Obrecht,Daniel
AU  - Williams,Glyn
AU  - Klumpp,Klaus
TI  - Use of a pharmacophore model to discover a new class of influenza endonuclease inhibitors
SN  - 0022-2623
PY  - 2003///0502
KW  - Animals
KW  - Antiviral Agents
KW  - chemical synthesis
KW  - Binding Sites
KW  - Butyrates
KW  - Cell Line
KW  - Combinatorial Chemistry Techniques
KW  - DNA-Directed RNA Polymerases
KW  - chemistry
KW  - Databases, Factual
KW  - Dogs
KW  - Endonucleases
KW  - antagonists & inhibitors
KW  - Enzyme Inhibitors
KW  - Heterocyclic Compounds, 3-Ring
KW  - Heterocyclic Compounds, 4 or More Rings
KW  - Influenza A virus
KW  - drug effects
KW  - Influenza B virus
KW  - Keto Acids
KW  - Models, Molecular
KW  - Phthalimides
KW  - Protein Binding
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm020334u
ER  -