Barreiro, Eliezer J

Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: a new class of potent and selective acetylcholinesterase inhibitors. [electronic resource] - Journal of medicinal chemistry Mar 2003 - 1144-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm020391n doi


Acetylcholinesterase--chemistry
Animals
Butyrylcholinesterase--chemistry
Cells, Cultured
Cerebral Cortex--cytology
Cholinesterase Inhibitors--chemical synthesis
Crystallography, X-Ray
Models, Molecular
Naphthyridines--chemical synthesis
Neuroprotective Agents--chemical synthesis
Pyrazoles--chemical synthesis
Pyridines--chemical synthesis
Rats
Rats, Wistar
Structure-Activity Relationship
Torpedo