TY  - GEN
AU  - Chester,John D
AU  - Joel,Simon P
AU  - Cheeseman,Susan L
AU  - Hall,Geoffrey D
AU  - Braun,Michael S
AU  - Perry,Jackie
AU  - Davis,Theresa
AU  - Button,Christopher J
AU  - Seymour,Matthew T
TI  - Phase I and pharmacokinetic study of intravenous irinotecan plus oral ciclosporin in patients with fuorouracil-refractory metastatic colon cancer
SN  - 0732-183X
PY  - 2003///0410
KW  - Administration, Oral
KW  - Adult
KW  - Aged
KW  - Antimetabolites, Antineoplastic
KW  - pharmacology
KW  - Antineoplastic Agents, Phytogenic
KW  - administration & dosage
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - Camptothecin
KW  - Colonic Neoplasms
KW  - blood
KW  - Cyclosporine
KW  - Drug Resistance, Neoplasm
KW  - Female
KW  - Fluorouracil
KW  - Humans
KW  - Infusions, Intravenous
KW  - Irinotecan
KW  - Male
KW  - Middle Aged
KW  - Neoplasm Staging
KW  - Treatment Outcome
N1  - Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1200/JCO.2003.08.049
ER  -