ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1. [electronic resource]
- The Journal of biological chemistry May 2003
- 18859-67 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M211696200 doi
Adaptor Proteins, Signal Transducing Base Sequence Blotting, Northern Blotting, Western Carrier Proteins--genetics Cell Cycle Proteins Cell Line Chromones--pharmacology Cycloheximide--pharmacology DNA-Binding Proteins--genetics Early Growth Response Protein 1 Enzyme Activation--drug effects Enzyme Inhibitors--pharmacology Gene Expression--drug effects Granulocyte-Macrophage Colony-Stimulating Factor--pharmacology Histamine--metabolism Histidine Decarboxylase--genetics Humans Hypotonic Solutions Immediate-Early Proteins JNK Mitogen-Activated Protein Kinases Kinetics MAP Kinase Kinase 4 Mitogen-Activated Protein Kinase 11 Mitogen-Activated Protein Kinase 8 Mitogen-Activated Protein Kinase Kinases--metabolism Mitogen-Activated Protein Kinases--antagonists & inhibitors Molecular Sequence Data Morpholines--pharmacology Mutation Phosphoinositide-3 Kinase Inhibitors Phosphoproteins--genetics Phosphorylation Phosphoserine--metabolism Promoter Regions, Genetic--genetics RNA, Messenger--analysis Repressor Proteins--genetics Response Elements Sirolimus--pharmacology Tetradecanoylphorbol Acetate--pharmacology Transcription Factors--genetics p38 Mitogen-Activated Protein Kinases