TY - GEN AU - Kim,Jong-M AU - Bae,Hae R AU - Park,Bong S AU - Lee,Je M AU - Ahn,Hee B AU - Rho,Jee H AU - Yoo,Kyung W AU - Park,Woo C AU - Rho,Sae H AU - Yoon,Hee S AU - Yoo,Young Hyun TI - Early mitochondrial hyperpolarization and intracellular alkalinization in lactacystin-induced apoptosis of retinal pigment epithelial cells SN - 0022-3565 PY - 2003///0530 KW - Acetylcysteine KW - analogs & derivatives KW - Animals KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Caspase 3 KW - Caspase Inhibitors KW - Caspases KW - biosynthesis KW - Cell Survival KW - Cells, Cultured KW - Cysteine Endopeptidases KW - Cysteine Proteinase Inhibitors KW - pharmacology KW - DNA KW - chemistry KW - Electrophoresis, Polyacrylamide Gel KW - Electrophysiology KW - Enzyme Inhibitors KW - Fluorescent Antibody Technique KW - Hydrogen-Ion Concentration KW - Membrane Potentials KW - Microscopy, Electron KW - Mitochondria KW - Multienzyme Complexes KW - Oligomycins KW - Pigment Epithelium of Eye KW - cytology KW - Poly Adenosine Diphosphate Ribose KW - Proteasome Endopeptidase Complex KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - Rats KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article UR - https://doi.org/10.1124/jpet.102.047811 ER -