The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. [electronic resource]
- Journal of neurochemistry Mar 2003
- 1173-83 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
0022-3042
10.1046/j.1471-4159.2003.01580.x doi
Acetylcysteine--therapeutic use Age Factors Amyloid beta-Peptides--biosynthesis Animals Antioxidants--therapeutic use Appetitive Behavior--drug effects Behavior, Animal--drug effects Blood-Brain Barrier--drug effects Brain--drug effects Cognition--drug effects Disease Models, Animal Male Maze Learning--drug effects Memory Disorders--drug therapy Mice Mice, Inbred Strains Mice, Neurologic Mutants Oxidative Stress--drug effects Specific Pathogen-Free Organisms Thioctic Acid--therapeutic use Treatment Outcome