TY - GEN AU - Ding,Zhongren AU - Kim,Soochong AU - Dorsam,Robert T AU - Jin,Jianguo AU - Kunapuli,Satya P TI - Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270 SN - 0006-4971 PY - 2003///0718 KW - 4-Chloromercuribenzenesulfonate KW - pharmacology KW - Adenosine Diphosphate KW - Amino Acid Sequence KW - Animals KW - Base Sequence KW - Binding Sites KW - CHO Cells KW - Cricetinae KW - Cyclic AMP KW - metabolism KW - Cysteine KW - DNA Primers KW - Humans KW - Inositol Phosphates KW - Kinetics KW - Membrane Proteins KW - Molecular Sequence Data KW - Purinergic P2 Receptor Antagonists KW - Receptors, Purinergic P2 KW - chemistry KW - Receptors, Purinergic P2Y1 KW - Receptors, Purinergic P2Y12 KW - Recombinant Proteins KW - antagonists & inhibitors KW - Sequence Alignment KW - Sequence Homology, Amino Acid KW - Sulfhydryl Compounds KW - Transfection N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1182/blood-2002-10-3027 ER -