TY - GEN AU - LaVallee,Theresa M AU - Zhan,Xiaoguo H AU - Johnson,Michelle S AU - Herbstritt,Chris J AU - Swartz,Glenn AU - Williams,Mark S AU - Hembrough,Wendy A AU - Green,Shawn J AU - Pribluda,Victor S TI - 2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway SN - 0008-5472 PY - 2003///0313 KW - 2-Methoxyestradiol KW - Adaptor Proteins, Signal Transducing KW - Animals KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - Breast Neoplasms KW - drug therapy KW - Carrier Proteins KW - biosynthesis KW - Caspases KW - metabolism KW - Cell Division KW - Drug Synergism KW - Endothelium, Vascular KW - cytology KW - Enzyme Activation KW - Estradiol KW - analogs & derivatives KW - Fas-Associated Death Domain Protein KW - Female KW - Humans KW - Isoenzymes KW - Membrane Glycoproteins KW - pharmacology KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - Receptors, TNF-Related Apoptosis-Inducing Ligand KW - Receptors, Tumor Necrosis Factor KW - antagonists & inhibitors KW - Signal Transduction KW - physiology KW - TNF-Related Apoptosis-Inducing Ligand KW - Transfection KW - Tumor Cells, Cultured KW - Tumor Necrosis Factor-alpha KW - Up-Regulation KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article ER -