TY - GEN AU - Krishnan,Sampathkumar AU - Chi,Eva Y AU - Wood,Stephen J AU - Kendrick,Brent S AU - Li,Cynthia AU - Garzon-Rodriguez,William AU - Wypych,Jette AU - Randolph,Theodore W AU - Narhi,Linda O AU - Biere,Anja Leona AU - Citron,Martin AU - Carpenter,John F TI - Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease alpha-synuclein fibrillogenesis SN - 0006-2960 PY - 2003///0407 KW - Amino Acid Substitution KW - genetics KW - Chromatography, High Pressure Liquid KW - Cross-Linking Reagents KW - metabolism KW - Dimerization KW - Humans KW - Hydrogen-Ion Concentration KW - Light KW - Nerve Tissue Proteins KW - Osmolar Concentration KW - Osmotic Pressure KW - Oxidation-Reduction KW - Oxidative Stress KW - Parkinson Disease KW - etiology KW - Protein Isoforms KW - Scattering, Radiation KW - Spectrometry, Mass, Electrospray Ionization KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization KW - Spectrophotometry, Ultraviolet KW - Synucleins KW - Temperature KW - Tyrosine KW - analogs & derivatives KW - alpha-Synuclein N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1021/bi026528t ER -