HIV-1 gp120-induced tubular epithelial cell apoptosis is mediated through p38-MAPK phosphorylation. [electronic resource]
- Molecular medicine (Cambridge, Mass.) Nov 2002
- 676-85 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
1076-1551
Adult Apoptosis--drug effects Blotting, Northern Blotting, Western CD4 Antigens--metabolism Caspase 3 Caspases--metabolism Cells, Cultured Dose-Response Relationship, Drug Enzyme Inhibitors--pharmacology Enzyme-Linked Immunosorbent Assay Epithelial Cells--metabolism HIV Envelope Protein gp120--pharmacology HIV-1 Humans Imidazoles--pharmacology Immunoenzyme Techniques In Situ Nick-End Labeling Kidney Tubules, Proximal--metabolism MAP Kinase Signaling System--drug effects Mitogen-Activated Protein Kinases--antagonists & inhibitors Peptide Fragments--immunology Phosphorylation Proliferating Cell Nuclear Antigen--metabolism Pyridines--pharmacology RNA, Messenger--metabolism p38 Mitogen-Activated Protein Kinases