Mensah-Osman, Edith J

2-[4-(7-chloro-2-quinoxalinyloxyphenoxy]-propionic acid (XK469), an inhibitor of topoisomerase (Topo) IIbeta, up-regulates Topo IIalpha and enhances Topo IIalpha-mediated cytotoxicity. [electronic resource] - Molecular cancer therapeutics Dec 2002 - 1321-6 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1535-7163


Antigens, Neoplasm
Blotting, Western
Culture Media, Serum-Free
DNA--metabolism
DNA Topoisomerases, Type II--metabolism
DNA-Binding Proteins
Enzyme Inhibitors--pharmacology
Etoposide--pharmacology
Humans
Immunohistochemistry
Leukemia, Lymphocytic, Chronic, B-Cell--blood
Microscopy, Confocal
Microscopy, Fluorescence
Neoplasm Transplantation
Protein Isoforms
Quinoxalines--pharmacology
Time Factors
Tumor Cells, Cultured
Up-Regulation
Waldenstrom Macroglobulinemia--drug therapy