TY - GEN AU - Zhong,Bin AU - Jiang,Kun AU - Gilvary,Danielle L AU - Epling-Burnette,Pearlie K AU - Ritchey,Connie AU - Liu,Jinhong AU - Jackson,Rosalind J AU - Hong-Geller,Elizabeth AU - Wei,Sheng TI - Human neutrophils utilize a Rac/Cdc42-dependent MAPK pathway to direct intracellular granule mobilization toward ingested microbial pathogens SN - 0006-4971 PY - 2003///0618 KW - Candida albicans KW - Cytoplasmic Granules KW - physiology KW - Enzyme Activation KW - drug effects KW - Enzyme Inhibitors KW - pharmacology KW - Flavonoids KW - Genes, Dominant KW - Humans KW - MAP Kinase Kinase 1 KW - MAP Kinase Signaling System KW - Mitogen-Activated Protein Kinase 1 KW - metabolism KW - Mitogen-Activated Protein Kinase 3 KW - Mitogen-Activated Protein Kinase Kinases KW - antagonists & inhibitors KW - Mitogen-Activated Protein Kinases KW - Mutagenesis, Site-Directed KW - Neutrophils KW - Phagocytosis KW - Phosphorylation KW - Protein Processing, Post-Translational KW - Protein Serine-Threonine Kinases KW - Recombinant Fusion Proteins KW - Transduction, Genetic KW - cdc42 GTP-Binding Protein KW - genetics KW - p21-Activated Kinases KW - rac1 GTP-Binding Protein KW - rho GTP-Binding Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1182/blood-2001-12-0180 ER -