TY - GEN AU - Chen,Jun AU - Freeman,Angela AU - Liu,Jihua AU - Dai,Qiang AU - Lee,Ruey-min TI - The apoptotic effect of HA14-1, a Bcl-2-interacting small molecular compound, requires Bax translocation and is enhanced by PK11195 SN - 1535-7163 PY - 2003///0512 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - Benzopyrans KW - Blotting, Western KW - Caspase Inhibitors KW - Caspases KW - metabolism KW - Cell Survival KW - Cell-Free System KW - Cells, Cultured KW - Coloring Agents KW - Cytochrome c Group KW - Cytosol KW - Dose-Response Relationship, Drug KW - Enzyme Inhibitors KW - HL-60 Cells KW - Humans KW - In Situ Nick-End Labeling KW - Isoquinolines KW - Mice KW - Microscopy, Fluorescence KW - Mitochondria KW - drug effects KW - Nitriles KW - Protein Transport KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - Subcellular Fractions KW - Tetrazolium Salts KW - Thiazoles KW - Time Factors KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -