Tong, Wei-Gang

Lipoxygenase inhibitors attenuate growth of human pancreatic cancer xenografts and induce apoptosis through the mitochondrial pathway. [electronic resource] - Molecular cancer therapeutics Sep 2002 - 929-35 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1535-7163


Animals
Annexin A5--pharmacology
Apoptosis
Arachidonate 12-Lipoxygenase--metabolism
Arachidonate 5-Lipoxygenase--metabolism
Arachidonic Acid--metabolism
Blotting, Western
Caspase 3
Caspase 7
Caspase 8
Caspase 9
Caspases--metabolism
Cell Division
Coloring Agents--pharmacology
Cytochrome c Group--metabolism
Cytosol--metabolism
DNA--metabolism
Humans
In Situ Nick-End Labeling
Lipoxygenase--pharmacology
Lipoxygenase Inhibitors--pharmacology
Male
Mice
Mice, Inbred BALB C
Mice, Nude
Mitochondria--metabolism
Myeloid Cell Leukemia Sequence 1 Protein
Neoplasm Proteins--metabolism
Neoplasm Transplantation
Pancreatic Neoplasms--enzymology
Poly(ADP-ribose) Polymerases--metabolism
Proto-Oncogene Proteins c-bcl-2--metabolism
Quinolines--pharmacology
Substrate Specificity
Time Factors
Tumor Cells, Cultured