Song, Lun

IL-6 inhibits apoptosis of human myeloma cell line XG-7 through activation of JAK/STAT pathway and up-regulation of Mcl-1. [electronic resource] - Ai zheng = Aizheng = Chinese journal of cancer Feb 2002 - 113-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't


Apoptosis--drug effects
DNA-Binding Proteins--physiology
Humans
Interleukin-6--pharmacology
Janus Kinase 2
Mitogen-Activated Protein Kinases--physiology
Multiple Myeloma--pathology
Myeloid Cell Leukemia Sequence 1 Protein
Neoplasm Proteins--biosynthesis
Phosphatidylinositol 3-Kinases--physiology
Protein-Tyrosine Kinases--physiology
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcl-2
STAT1 Transcription Factor
STAT3 Transcription Factor
Signal Transduction
Trans-Activators--physiology
Tumor Cells, Cultured
Up-Regulation