TY  - GEN
AU  - Blat,Yuval
AU  - Meredith,Jere E
AU  - Wang,Qian
AU  - Bradley,Jodi D
AU  - Thompson,Lorin A
AU  - Olson,Richard E
AU  - Stern,Andrew M
AU  - Seiffert,Dietmar
TI  - Mutations at the P1' position of Notch1 decrease intracellular domain stability rather than cleavage by gamma-secretase
SN  - 0006-291X
PY  - 2003///0124
KW  - Acetylcysteine
KW  - analogs & derivatives
KW  - Amyloid Precursor Protein Secretases
KW  - Animals
KW  - Aspartic Acid Endopeptidases
KW  - Cell Line
KW  - Cell-Free System
KW  - Cells, Cultured
KW  - Cysteine Proteinase Inhibitors
KW  - metabolism
KW  - Endopeptidases
KW  - Fibroblasts
KW  - cytology
KW  - Humans
KW  - Membrane Proteins
KW  - genetics
KW  - Mice
KW  - Mice, Knockout
KW  - Molecular Structure
KW  - Mutation
KW  - Protein Structure, Tertiary
KW  - Receptor, Notch1
KW  - Receptors, Cell Surface
KW  - Transcription Factors
KW  - Valine
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/s0006-291x(02)02705-5
ER  -