Brown, Gavin D <br/><br/>
Antitumor imidazotetrazines. 40. Radiosyntheses of [4-11C-carbonyl]- and [3-N-11C-methyl]-8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (temozolomide) for positron emission tomography (PET) studies.  [electronic resource] 

 -  Journal of medicinal chemistry  Dec 2002 
 - 5448-57 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm020921f  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Brain Diseases--diagnostic imaging<br/>Carbon Radioisotopes<br/>Cyclization<br/>Dacarbazine--analogs & derivatives<br/>Gas Chromatography-Mass Spectrometry<br/>Humans<br/>Isotope Labeling<br/>Magnetic Resonance Spectroscopy<br/>Parietal Lobe--diagnostic imaging<br/>Prodrugs--chemical synthesis<br/>Structure-Activity Relationship<br/>Temozolomide<br/>Tomography, Emission-Computed