Azzouz, Mimoun <br/><br/>
Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease.  [electronic resource] 

 -  The Journal of neuroscience : the official journal of the Society for Neuroscience  Dec 2002 
 - 10302-12 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1529-2401 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Aromatic-L-Amino-Acid Decarboxylases--administration & dosage<br/>Catecholamines--metabolism<br/>Cells, Cultured<br/>Corpus Striatum--drug effects<br/>Disease Models, Animal<br/>Dopamine--biosynthesis<br/>GTP Cyclohydrolase--administration & dosage<br/>Gene Expression--drug effects<br/>Gene Transfer Techniques<br/>Genes--genetics<br/>Genetic Therapy--methods<br/>Genetic Vectors--administration & dosage<br/>Humans<br/>Kidney--cytology<br/>Lentivirus--genetics<br/>Male<br/>Neurons--cytology<br/>Oxidopamine<br/>Parkinsonian Disorders--chemically induced<br/>Rats<br/>Rats, Wistar<br/>Recovery of Function--drug effects<br/>Transgenes<br/>Treatment Outcome<br/>Tyrosine 3-Monooxygenase--administration & dosage