TY - GEN AU - Horng,Tiffany AU - Barton,Gregory M AU - Flavell,Richard A AU - Medzhitov,Ruslan TI - The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors SN - 0028-0836 PY - 2002///1212 KW - Adaptor Proteins, Signal Transducing KW - Animals KW - Antigens, Differentiation KW - genetics KW - Cell Differentiation KW - drug effects KW - Cell Division KW - Cells, Cultured KW - Cytokines KW - biosynthesis KW - Dendritic Cells KW - cytology KW - Drosophila Proteins KW - Female KW - Immunity, Innate KW - Interleukin-1 KW - pharmacology KW - Interleukin-18 KW - Lipopolysaccharides KW - Macrophages KW - Male KW - Membrane Glycoproteins KW - metabolism KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Mitogen-Activated Protein Kinases KW - Myeloid Differentiation Factor 88 KW - NF-kappa B KW - Receptors, Cell Surface KW - Receptors, Immunologic KW - Receptors, Interleukin-1 KW - deficiency KW - Signal Transduction KW - Spleen KW - Substrate Specificity KW - Toll-Like Receptor 1 KW - Toll-Like Receptor 2 KW - Toll-Like Receptor 4 KW - Toll-Like Receptor 5 KW - Toll-Like Receptor 7 KW - Toll-Like Receptors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1038/nature01180 ER -