TY  - GEN
AU  - Morpurgo,Margherita
AU  - Monfardini,Cristina
AU  - Hofland,Leo J
AU  - Sergi,Mauro
AU  - Orsolini,Paolo
AU  - Dumont,Jean M
AU  - Veronese,Francesco M
TI  - Selective alkylation and acylation of alpha and epsilon amino groups with PEG in a somatostatin analogue: tailored chemistry for optimized bioconjugates
SN  - 1043-1802
PY  - 2003///0516
KW  - Acylation
KW  - Alkylation
KW  - Amino Acid Sequence
KW  - Animals
KW  - Cells, Cultured
KW  - Chromatography, High Pressure Liquid
KW  - Circular Dichroism
KW  - Growth Hormone
KW  - metabolism
KW  - Inhibitory Concentration 50
KW  - Male
KW  - Molecular Structure
KW  - Pituitary Gland, Anterior
KW  - cytology
KW  - Polyethylene Glycols
KW  - chemistry
KW  - Rats
KW  - Somatostatin
KW  - analogs & derivatives
KW  - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/bc0100511
ER  -