MacKenzie, A Roderick <br/><br/>
Structure-activity relationships of 1-alkyl-5-(3,4-dichlorophenyl)- 5-[2-[(3-substituted)-1-azetidinyl]ethyl]-2-piperidones. 1. Selective antagonists of the neurokinin-2 receptor.  [electronic resource] 

 -  Journal of medicinal chemistry  Nov 2002 
 - 5365-77 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm0209331  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Azetidines--chemical synthesis<br/>CHO Cells<br/>Cricetinae<br/>Drug Stability<br/>Humans<br/>In Vitro Techniques<br/>Microsomes, Liver--metabolism<br/>Muscle Contraction--drug effects<br/>Muscle, Smooth--drug effects<br/>Piperazines--chemical synthesis<br/>Piperidones--chemical synthesis<br/>Pulmonary Artery--drug effects<br/>Rabbits<br/>Radioligand Assay<br/>Receptors, Neurokinin-2--antagonists & inhibitors<br/>Receptors, Neurokinin-3--metabolism<br/>Stereoisomerism<br/>Structure-Activity Relationship