TY - GEN AU - Pamment,Jessica AU - Ramsay,Eleanor AU - Kelleher,Michael AU - Dornan,David AU - Ball,Kathryn L TI - Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway SN - 0950-9232 PY - 2002///1212 KW - Androstadienes KW - pharmacology KW - Ataxia Telangiectasia KW - genetics KW - Ataxia Telangiectasia Mutated Proteins KW - Cell Cycle Proteins KW - Cells, Cultured KW - metabolism KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Cyclins KW - physiology KW - Cycloheximide KW - DNA KW - drug effects KW - DNA Damage KW - DNA-Binding Proteins KW - biosynthesis KW - Enzyme Inhibitors KW - Etoposide KW - toxicity KW - Fibroblasts KW - Gamma Rays KW - adverse effects KW - Genes, Reporter KW - Genes, p53 KW - Humans KW - Interferon Regulatory Factor-1 KW - Melanoma KW - pathology KW - Phosphatidylinositol 3-Kinases KW - Phosphoinositide-3 Kinase Inhibitors KW - Phosphoproteins KW - Phosphorylation KW - Poly I-C KW - Protein Processing, Post-Translational KW - Protein Serine-Threonine Kinases KW - deficiency KW - Protein Synthesis Inhibitors KW - RNA, Messenger KW - Recombinant Fusion Proteins KW - Signal Transduction KW - Transcription, Genetic KW - Tumor Cells, Cultured KW - Tumor Suppressor Protein p53 KW - Tumor Suppressor Proteins KW - Wortmannin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/sj.onc.1205981 ER -