TY - GEN AU - Slater,Martin J AU - Andrews,David M AU - Baker,Graham AU - Bethell,Susanne S AU - Carey,Seb AU - Chaignot,Helene AU - Clarke,Berwyn AU - Coomber,Barry AU - Ellis,Malcolm AU - Good,Andrew AU - Gray,Norman AU - Hardy,George AU - Jones,Paul AU - Mills,Gail AU - Robinson,Ed TI - Design and synthesis of ethyl pyrrolidine-5,5-trans-lactams as inhibitors of hepatitis C virus NS3/4A protease SN - 0960-894X PY - 2003///0520 KW - Amino Acid Sequence KW - Carrier Proteins KW - antagonists & inhibitors KW - Drug Design KW - Hepacivirus KW - drug effects KW - Humans KW - Inhibitory Concentration 50 KW - Intracellular Signaling Peptides and Proteins KW - Lactams KW - chemical synthesis KW - Microbial Sensitivity Tests KW - Pyrrolidines KW - Serine Proteinase Inhibitors KW - Stereoisomerism KW - Structure-Activity Relationship KW - Viral Nonstructural Proteins KW - Viral Proteins N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/s0960-894x(02)00789-8 ER -