Slater, Martin J <br/><br/>
Design and synthesis of ethyl pyrrolidine-5,5-trans-lactams as inhibitors of hepatitis C virus NS3/4A protease.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Dec 2002 
 - 3359-62 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/s0960-894x(02)00789-8  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Carrier Proteins--antagonists & inhibitors<br/>Drug Design<br/>Hepacivirus--drug effects<br/>Humans<br/>Inhibitory Concentration 50<br/>Intracellular Signaling Peptides and Proteins<br/>Lactams--chemical synthesis<br/>Microbial Sensitivity Tests<br/>Pyrrolidines--chemical synthesis<br/>Serine Proteinase Inhibitors--chemical synthesis<br/>Stereoisomerism<br/>Structure-Activity Relationship<br/>Viral Nonstructural Proteins--antagonists & inhibitors<br/>Viral Proteins--antagonists & inhibitors