Singh, Ishwar

Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 9: comparison of acetoxy 4-methylcoumarins and other polyphenolic acetates reveal the specificity to acetoxy drug: protein transacetylase for pyran carbonyl group in proximity to the oxygen heteroatom. [electronic resource] - Bioorganic & medicinal chemistry Dec 2002 - 4103-11 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0968-0896

10.1016/s0968-0896(02)00257-2 doi


Acetates--chemistry
Acetyltransferases--chemistry
Animals
Coumarins--chemistry
Flavonoids
Male
Microsomes, Liver--enzymology
Molecular Structure
NADH Dehydrogenase--drug effects
Phenols--chemistry
Polymers--chemistry
Polyphenols
Pyrans--chemistry
Rats
Rats, Wistar
Structure-Activity Relationship
Substrate Specificity