Lange, Thoralf <br/><br/>
High levels of BAX, low levels of MRP-1, and high platelets are independent predictors of response to imatinib in myeloid blast crisis of CML.  [electronic resource] 

 -  Blood  Mar 2003 
 - 2152-5 p.  digital 
<br/><br/> Publication Type: Clinical Trial; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0006-4971 
<br/><br/><label>Standard No.: </label>10.1182/blood-2002-05-1366  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Antigens, CD34--analysis<br/>Antineoplastic Agents--therapeutic use<br/>Apoptosis--genetics<br/>Benzamides<br/>Blast Crisis--drug therapy<br/>Chemokines, CC--genetics<br/>Drug Resistance, Neoplasm--genetics<br/>Drug Screening Assays, Antitumor<br/>Female<br/>Gene Expression<br/>Humans<br/>Imatinib Mesylate<br/>Leukemia, Myelogenous, Chronic, BCR-ABL Positive--drug therapy<br/>Male<br/>Middle Aged<br/>Piperazines--therapeutic use<br/>Platelet Count<br/>Proto-Oncogene Proteins--genetics<br/>Proto-Oncogene Proteins c-bcl-2<br/>Pyrimidines--therapeutic use<br/>RNA, Messenger--analysis<br/>Remission Induction<br/>Stem Cell Transplantation<br/>Transplantation, Homologous<br/>Tumor Cells, Cultured<br/>bcl-2-Associated X Protein