TY - GEN AU - Coutant,Alexandre AU - Rescan,Claude AU - Gilot,David AU - Loyer,Pascal AU - Guguen-Guillouzo,Christiane AU - Baffet,Georges TI - PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival SN - 0270-9139 PY - 2002///1209 KW - Animals KW - Carrier Proteins KW - metabolism KW - Cell Division KW - physiology KW - Cell Survival KW - Cells, Cultured KW - Cyclin D1 KW - DNA KW - biosynthesis KW - Enzyme Inhibitors KW - pharmacology KW - Epidermal Growth Factor KW - G1 Phase KW - Hepatocytes KW - cytology KW - Insulin KW - Intracellular Signaling Peptides and Proteins KW - MAP Kinase Kinase Kinase 1 KW - MAP Kinase Signaling System KW - drug effects KW - Male KW - Mitogen-Activated Protein Kinases KW - Phosphatidylinositol 3-Kinases KW - Phosphoinositide-3 Kinase Inhibitors KW - Phosphoproteins KW - Phosphorylation KW - Protein Biosynthesis KW - Protein Kinases KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - Rats KW - Rats, Sprague-Dawley KW - S Phase KW - TOR Serine-Threonine Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1053/jhep.2002.36160 ER -