Coutant, Alexandre <br/><br/>
PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.  [electronic resource] 

 -  Hepatology (Baltimore, Md.)  Nov 2002 
 - 1079-88 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0270-9139 
<br/><br/><label>Standard No.: </label>10.1053/jhep.2002.36160  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Carrier Proteins--metabolism<br/>Cell Division--physiology<br/>Cell Survival--physiology<br/>Cells, Cultured<br/>Cyclin D1--metabolism<br/>DNA--biosynthesis<br/>Enzyme Inhibitors--pharmacology<br/>Epidermal Growth Factor--pharmacology<br/>G1 Phase--physiology<br/>Hepatocytes--cytology<br/>Insulin--metabolism<br/>Intracellular Signaling Peptides and Proteins<br/>MAP Kinase Kinase Kinase 1<br/>MAP Kinase Signaling System--drug effects<br/>Male<br/>Mitogen-Activated Protein Kinases--metabolism<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Phosphoproteins--metabolism<br/>Phosphorylation<br/>Protein Biosynthesis<br/>Protein Kinases--metabolism<br/>Protein Serine-Threonine Kinases--metabolism<br/>Proto-Oncogene Proteins--metabolism<br/>Proto-Oncogene Proteins c-akt<br/>Rats<br/>Rats, Sprague-Dawley<br/>S Phase--physiology<br/>TOR Serine-Threonine Kinases