Smith, Martyn T

Low NAD(P)H:quinone oxidoreductase activity is associated with increased risk of leukemia with MLL translocations in infants and children. [electronic resource] - Blood Dec 2002 - 4590-3 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0006-4971

10.1182/blood-2001-12-0264 doi


Acute Disease
Amino Acid Substitution
Child, Preschool
Chromosomes, Human, Pair 11--ultrastructure
Chromosomes, Human, Pair 18--ultrastructure
DNA-Binding Proteins--genetics
Ethnicity--genetics
Female
Genetic Predisposition to Disease
Histone-Lysine N-Methyltransferase
Humans
Infant
Infant, Newborn
Leukemia--enzymology
Leukemia, Myeloid--enzymology
Male
Mutation, Missense
Myeloid-Lymphoid Leukemia Protein
NAD(P)H Dehydrogenase (Quinone)--deficiency
Neoplasm Proteins--deficiency
Neoplastic Stem Cells--enzymology
Odds Ratio
Point Mutation
Precursor Cell Lymphoblastic Leukemia-Lymphoma--enzymology
Proto-Oncogenes
Risk Factors
Transcription Factors
Translocation, Genetic