Rush, Catherine

Efficient priming of CD4+ and CD8+ T cells by DNA vaccination depends on appropriate targeting of sufficient levels of immunologically relevant antigen to appropriate processing pathways. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Nov 2002 - 4951-60 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-1767

10.4049/jimmunol.169.9.4951 doi


Animals
Antigen Presentation--genetics
Antigens, Differentiation, T-Lymphocyte--biosynthesis
CD4-Positive T-Lymphocytes--cytology
CD8-Positive T-Lymphocytes--cytology
COS Cells
Cell Division--genetics
Cell Line
Clone Cells
Epitopes, T-Lymphocyte--immunology
Humans
Hybridomas--immunology
Immunoglobulin G--biosynthesis
Immunologic Memory--genetics
Injections, Intramuscular
Interferon-gamma--biosynthesis
Introns--genetics
Lymphocyte Activation--genetics
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Transgenic
Organ Specificity--genetics
Ovalbumin--biosynthesis
Plasmids--immunology
Recombinant Fusion Proteins--genetics
Signal Transduction--genetics
Transfection
Vaccines, DNA--administration & dosage