Mechanism of antiandrogen action: key role of hsp90 in conformational change and transcriptional activity of the androgen receptor. [electronic resource]
- Biochemistry Oct 2002
- 11824-31 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0006-2960
10.1021/bi0259150 doi
Active Transport, Cell Nucleus--drug effects Androgen Antagonists--chemistry Animals Benzoquinones COS Cells Cell Line Cell Nucleus--chemistry Endopeptidases Green Fluorescent Proteins HSP90 Heat-Shock Proteins--antagonists & inhibitors Humans Hydrolysis Kinetics Lactams, Macrocyclic Luminescent Proteins--genetics Microscopy, Fluorescence Plasmids Protein Conformation Quinones--pharmacology Receptors, Androgen--chemistry Trans-Activators--chemistry Transfection