Suschek, Christoph Viktor

Revisiting an old antimicrobial drug: amphotericin B induces interleukin-1-converting enzyme as the main factor for inducible nitric-oxide synthase expression in activated endothelia. [electronic resource] - Molecular pharmacology Oct 2002 - 936-46 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0026-895X

10.1124/mol.62.4.936 doi


Amphotericin B--pharmacology
Animals
Antifungal Agents--pharmacology
Caspase 1--biosynthesis
Cytokines--metabolism
Endothelium, Vascular--drug effects
Enzyme Induction--drug effects
Gene Expression--drug effects
Humans
Interleukin-1--metabolism
Nitric Oxide Synthase--biosynthesis
Nitric Oxide Synthase Type II
Promoter Regions, Genetic--physiology
RNA, Messenger--biosynthesis
Rats
Tumor Necrosis Factor-alpha--metabolism